Evaluation of cumulative properties of the complex "KN-73"

This article is devoted to the study of the possibility of using two different types of carrageenan as a phlogogenic factor for modeling inflammatory edema in order to study the antiinflammatory properties of new drugs. In the course of research, it was found that k-carrageenan, when administered subplantarly, leads to the development of necrosis in the tail region, therefore, cannot be used as an inducer of inflammation. At the same time, subplantar inoculations of κ-carrageenan cause a pronounced local inflammatory reaction, accompanied by increases in limb volume, hyperemia and hyperthermia, which is why it can be used to model "carrageenan edema".