Testing of delivery system for transcatheter mitral valve implantation

Aim. The aim of the study was to evaluate a prototype of a delivery system for transcatheter mitral valve replacement in vitro and in laboratory animal implantation. Methods. The prototypes of the delivery system and transcatheter mitral valve prosthesis were evaluated in vitro in an isolated pig heart using transapical access. In an experiment on a large laboratory animal implantation was performed using transatrial access. Results. It was found out that the prototype of the delivery system allows to adequately deliver and release the transcatheter prosthesis in implantation zone using transatrial and transapical approaches without frame deformation and valve dysfunction. Conclusion. The delivery system prototype for transcatheter mitral valve replacement demonstrated satisfactory characteristics during in vitro experiment and large laboratory animal implantation.