Alteration of bacterial biological properties of Staphylococcus epidermidis 33 as a result of vancomycin resistance formation

This work considers several biological peculiarities of coagulase-negative staphylococci occurring as a result of their resistance formation to glycopeptide antibiotic vancomycin. It was found that selected strain Staphylococcus epidermidis 33 Vanr was characterized by lowering in biomass accumulation while cultivating on rich nutrient medium, developing of multiple antibiotic resistance, marked decrease in cell surface hydrophobicity, phospholipid accumulation in cell membranes and declining in sensitivity to cationic peptide warnerin.