The change in the concentration of osteotropic hormones, osteocalcin, stress-group hormones in treatment of trans- and intertrochanteric fractures

The concentration of osteocalcin bone marker, that of osteotropic hormones and stress-group ones (ACTH, aldosterone, hydrocortisone) as well as that the concentration of growth hormone and cyclic nucleotides has been determined during treatment of 24 patients with trans- and intertrochanteric fractures using the Ilizarov method. The concentration of osteocalcin 3-5-fold increased for active reparative process. Among stress-group hormones ACTH concentration 7-fold increased from the early hours after fracture and decreased quickly within some days. Parathyrine content increased simultaneously. Calcitonin and somatotropin concentration increased after parathyrine content decrease. The dynamics of cyclic nucleotide change reflects reparative process activity