Antioxidant and anti-inflammatory cytokine indicators change in patients with calculous cholecystitis

In recent years, cytokine and antioxidant parameters have been widely studied in various diseases of the gastrointestinal tract, however, features of cytokine profile in patients with cholecystitis and gastritis have not been studied enough. In this regard, it is appropriate and important to study changes in the parameters of antioxidants and anti-inflammatory cytokines in patients with calculous cholecystitis. Research purpose: to determine the relationship between changes in the antioxidant status in gastrointestinal tract diseases. Research materials and methods: our study presents the results of an analysis of the assessment of the level of anti-inflammatory cytokines and antioxidants depending on the form of cholecystitis on the first day after surgery. Research results: based on the fact that in severe diseases there is a change in the level of enzymatic parameters in bile, we obtained and analyzed laboratory data on the content of the antioxidant status in patients. Conclusions: a comparative analysis of antioxidants and cytokines content showed changes in amount of superoxide dismutase and interleukin 1, the rest of indicators were normal.