The change in microflora specific composition in patients with chronic osteomyelitis during treatment

271 samples of wound and fistula discharge in 106 patients with chronic osteomyelitis have been analyzed. 458 strains of gram-positive and gram-negative bacteria have been isolated. The representatives of Staphylococcus family accounted for the most density (53,9%) of the total structure of the microorganisms isolated, and among these representatives coagulase-positive staphylococci (S. aureus and S. intermedius) dominated. Among the cultures isolated non-fermentating bacteria were the second (18,1%). The number of P. aeruginosa strains isolated increased in the first month after surgery, and other non-fermentating bacteria were added. The number of other gram-positive microorganisms nearly 3-fold increased, but the number of S. aureus, St. pyogenes and Proteus spp. Strains isolated decreased