Haemodynamic changes in alcohol-receiving animals under the influence of new structural analogues GABA - RGPU-147 and RGPU-195 compounds
Автор: Perfilova V.N., Tjurenkov I.N., Berestovizkaja V.M., Vasiljeva O.S., Sergeev S.I.
Журнал: Волгоградский научно-медицинский журнал @bulletin-volgmed
Рубрика: Фармакология токсикология
Статья в выпуске: 2 (26), 2010 года.
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Tested RGPU-147, RGPU-195-compounds and medicinal preparations such as phenibut and piracetam reduce the toxic effect of ethanol on the heart. Contractility disorders and heart pumping ability are marked less in those animals which received compounds listed above, than in a control group of alcohol-receiving animals. That is seen in elevated indices of SV, MVB, VEB, LVB, CB, RDI and decrease in TEMBV, SVR. The effect of RGPU-147 and RGPU-195 compounds on haemodynamic indices is compared with phenibut and piracetam
Chronic alcoholic intoxication, structural analogues gaba, haemodynamic parameters
Короткий адрес: https://sciup.org/142148826
IDR: 142148826
