Changes of volumes of structural components of a great saphenous vein with age and in varicose disease

The purpose of this study is to assess the extent of morphological changes in the structural components of the great saphenous vein in individuals of different age groups in norm and in varicose veins by morphometry of their volume fractions. The work was performed on autopsy material of 55 people who died at the age of 25 to 89 years, who had no pathological changes in the wall of the examined of the great saphenous veins at the time of death. To study of changes in the wall of the great saphenous vein in individuals of different age groups in varicose disease, fragments of veins removed during phlebotomy in 80 patients with varicose veins were used. The study of volume fractions structural components in individuals of different age groups showed that the volume of the inner shell - (further -tunica intima - TI) and the volume of the capillary network in the middle shell (hereinafter - tunica media - TM) decreased with age, while the volume of the muscular component in the circular layer of TM, as the age of patients did not change, and the content of longitudinal bundles of smooth muscle cells in the outer shell (further tunica externa - TE) increased...