Changes in the level of cortisol in young and old rats after light desynchronization

Biological rhythm disturbances can be caused not only by external influences, but also by disorders of certain organs. The causes of dysrhythmia, or disturbances in the rhythm of physiological functions, are extremely diverse, but non-specific changes in the circadian rhythm so often accompany pathological and pre-pathological conditions, in connection with which desynchronization of the rhythms of physiological functions has diagnostic significance and can be the cause of premature aging of a person. Until now, there is a lack of information on neuroimmunoendocrine changes that accompany light desynchronization - one of the signs of disruption of the central nervous system. To study the effect of light desynchronization on neuroendocrine regulation of physiological processes in the development of aging of the organism, we have implemented the following research areas: Study of the effect of light desynchronization of glucocorticoids, hormones of the hypothalamic-pituitary-adrenal system on the degree of aging processes.