A study of anxiolytic activity of new diazepinobenzimidazoles in the elevated plus maze test

Автор: Taran A.S., Maltsev D.V., Yakovlev D.S., Karavaeva T.V., Tkachenko Yu. O., Divaeva L.N., Morkovnik A.S., Kuzmenko T.A.

Журнал: Волгоградский научно-медицинский журнал @bulletin-volgmed

Рубрика: Фармакология токсикология

Статья в выпуске: 1 (53), 2017 года.

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This article provides the data on anxiolytic activity of new diazepinobenzimidazoles - a combination of two privileged structures. We have shown that have the studied parameters of DAB-7 and DAB-19 (latency to enter the open arms, entries in open arms and time spent in open arms) show no significant differences as compared to Diazepam as a reference anxiolytic drug. Therefore, we can conclude the high level of anxiolytic activity of these compounds.

Benzodiazepine, benzimidazole, diazepine benzimidazole, anxiolytic, elevated plus maze

Короткий адрес: https://sciup.org/142149207

IDR: 142149207

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