Study of biochemical and morphofunctional parameters in NSAID gastropathies

This study includes 78 patients with gastropathy of various etiology on the basis of which they were divided into groups with signs of inflammatory morphological changes and expressions of atrophy of the gastric mucosa and the parameters of homeostasis ( protein metabolism, electrolyte levels in the blood, enzymes of the pancreatic gland, indicator enzymes, hormonal level and coagulogram) were studied. The most marked changes in the homeostasis parameters looking like dysproteinemia, increase in the level of thyroid hormones, reduction of the prothrombine index) was noted in the group of patients with multifocal atrophic gastritis. The suggestion has been proposed that the above-shown changes of these parameters may be predictors of the pretumor neoplasms.