Study of electro-physical, rheological properties on the background of investigating iron metabolism in patients with gastric cancer

Автор: Labadze E., Narsia N., Tsalugelashvili A., Saldanha C., Kuchava G., Momtselidze N., Mantskava M.

Журнал: Российский журнал биомеханики @journal-biomech

Статья в выпуске: 2 (96) т.26, 2022 года.

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It is crucial to conduct research on clinical parameters of different body systems in gastric cancer as it is one of the most serious diseases in the modern world. The aim of our work was to study the rheological properties of blood in gastric cancer, along with the electrophysical properties of blood and iron metabolism in patients with gastric cancer. The research methods were modern and innovative. The study included patients with stomach cancer and a control group of healthy volunteers. The average age in the studied groups was similar. In all cases participants’ informed consent was obtained. In patients with gastric cancer before surgery the iron and hemoglobin levels were low, transferrin and ferritin remained within normal limits. On the 7th day after the operation, ferritin increased twice, hemoglobin was close to control values. Transferrin and iron remained reduced on the 7th postoperative day. The erythrocyte aggregability index in patients with gastric cancer before surgery was 1.5 times higher compared to the control group. On the 7th day after the operation, the erythrocyte aggregability index improved and increased by only 30 % compared to the control. The index of electrophysical properties in gastric cancer before surgery was changed compared to control values, on the 7th day after surgery, it was also changed. This approach, along with a thorough study of these routine analyzes in gastric cancer, is very important. It turned out that the seven-day postoperative interval was insufficient to normalize the studied parameters. The analysis of such data will make it possible to personalize the therapy of patients with stomach cancer, which is very important for each patient and public health in general.

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Rbc aggregation, electroclinical blood property, iron, transferrin, ferritin

Короткий адрес: https://sciup.org/146282493

IDR: 146282493   |   DOI: 10.15593/RZhBiomeh/2022.2.08

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