Assessment of markers of hemostasis and endothelial dysfunction in patients with progressive obliterating lower limb atherosclerosis

Автор: Korymasov E.A., Krivoshchekov E.P., Kazantsev A.V., Pribytkov D.L., Zolotarev P.N.

Журнал: Вестник медицинского института "РЕАВИЗ": реабилитация, врач и здоровье @vestnik-reaviz

Рубрика: Клиническая медицина

Статья в выпуске: 3 (45), 2020 года.

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We performed a comprehensive evaluation of the hemostatic system and markers of endothelial dysfunction in patients with obliterating lower limb atherosclerosis involving the femoral-popliteal-tibial segment. Progressive course of obliterating atherosclerosis is associated with hypercoagulation (increased platelet aggregation activity, shortened aPTT, PT, TT, increased levels of fibrinogen, SFMCs, and D-dimer), as well as with endothelial dysfunction (increased levels of endothelin-1, von Willebrand factor, homocysteine, and C-reactive protein).

Lower limb atherosclerosis, hemostatic system, hyperhomocysteinemia, endothelial dysfunction

Короткий адрес: https://sciup.org/143172351

IDR: 143172351

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