The study of the behavior of animals in the conditions of influence of chronic normobaric hypoxia and the way of its correction

In the above scientific review on the experimental rat model, the effect of reducing the oxygen fraction by 6% on the functional state of the central nervous system was studied. The aim of the study was to clarify the role of chronic hypoxic effects on the functional state of the central nervous system. Qualitative analysis of adaptation mechanisms was assessed by behavioral indicators obtained by generally accepted research methods in the open field and elevated plus-maze tests. The tests were carried out twice: the day before the hypoxic exposure and 21 days after exposure to the hypoxic factor. Evaluation of the emotional state, motor and research the activity of experimental animals was studied according to the nature of their behavior in the open field, elevated plus-maze tests. It is noted that the drug cytoflavin at a dose of 135 mg / kg has a neuroprotective effect. In an experimental model of normobaric hypoxia, cytoflavin has a regulating effect on the functional state of the central nervous system. The introduction of the compound reduces the emotional lability of experimental rats, increases the exploratory activity, and also has a protective and anxiolytic effect. This effect of the analyzed drug on the behavioral reactions of animals under hypoxic conditions determines its role in antihypoxic action.