Studying the role of screening research in the elimination of viral hepatitis B

Early diagnosis of viral hepatitis B (HBV) plays a key role in reducing the incidence and preventing complications such as cirrhosis and hepatocellular carcinoma. In the 2000s, the incidence of HBV in the Kyrgyz Republic was 5.7%, but as a result of mass vaccination and preventive measures, seroprevalence decreased to 3.07% by 2024. This indicates a transition from high to intermediate endemicity, although regional differences remain. Serological tests for HBsAg and PCR studies remain the main diagnostic tools. The effectiveness of vaccination is confirmed by minimal seroprevalence among children and adolescents. For further control of HBV, it is proposed to expand screening programs, strengthen preventive measures and introduce modern diagnostic methods.