Studying of toksikobiologichesky properties of potential pro-biotic microorganisms in the conditions of in vitro

It was found that when exposed to cell culture potential probiotic drug KPM-2 in the group with a concentration of microorganisms 2x10-11 CFU / ml, cell viability was less by 24.5% compared with the control, and when exposed to a potential probiotic drug KPM-10 in a concentration of 2x10-11 CFU / ml-by 39.5%, respectively. Proliferative activity when exposed to cell culture probiotic KPM-2 at a concentration of 2x10-11 CFU / ml decreased by 48.5%, when exposed to a potential drug KPM-10 at a concentration of 2x10-11 CFU/ml-by 71.6% in comparison with the control group. The data obtained by us indicate that the potential probiotic drug KPS-2 has lower cytotoxic properties when exposed to primary cell cultures compared to the drug KPM-10. Therefore, it is advisable to further study the drug KPM-2 as a probiotic drug.