Efficacy and safety of monotherapy with trimetazidine and isosorbide dinitrate retard and their combination in patients having stable angina pectoris combined with arterial hypotension

Автор: Rebrova N.V., Idrissova Ye.M., Shishkina A.A., Gouzeyeva T.V., Demesheva I.V., Vorobyeva E.V., Khamedova M. Sh., Karpov R.S.

Журнал: Сибирский журнал клинической и экспериментальной медицины @cardiotomsk

Рубрика: Клинические исследования

Статья в выпуске: 1 т.22, 2007 года.

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Antianginal efficacy and safety of trimetazidine (T), isosorbide dinitrate retard (IDR) and their combination (T+IDR) were studied in a randomized, single-blind study in 52 patients with combined stable angina pectoris and arterial hypotension (Hpts) and in 37 normotensive patients with angina of effort (Npts). Combined therapy efficacy was higher than antianginal activity of monotherapy of T or IDR in 12 weeks in Hpts. Side effects of drugs were observed: T - in 3% (p

Stable angina, trimetazidine, isosorbide dinitrate retard, combination therapy, arterial hypertension

Короткий адрес: https://sciup.org/14918642

IDR: 14918642

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