Rituximab treatment efficacy in a patient with systemic lupus erythematosus with severe thrombocytopenia

The article presents a clinical case of systemic lupus erythematosus with severe thrombocytopenia in a 55 year old patient. The standard therapy of usage of high doses of glucocorticoids, cyclophosphamide and intravenous im-munoglobulin was not effective. Application of Rituximab improved the course of disease, decreased the severity of thrombocytopenia, led to disappearance of leucopenia and anemia.