Endocrinic control of reparative process during bone intersegmental defect filling in the knee region using transosseous osteosynthesis technique

Changes of the following hormones in blood serum were assessed: sokmatotropin, calcitonin, parathyrine, insulin and cyclic nucleotides - 3´5´adenisinemonophosphate and 3´5´guanosine phosphate in 12 patients with defects of bone articular ends, forming the knee, before, during and after reconstructive-and-restorative surgeries on the basis of transosseous osteosynthesis.