Endothelium as a target of pathological effects of viral infection

The review article analyzes in detail the data obtained as a result of experimental and clinical studies on the interaction of various viruses with the endothelium and endocardium. The issues of the impact of a viral infection on endothelial cells, possible mechanisms of their damage, as well as the activation of pathological cascades of intra-vascular thrombosis, acute respiratory distress syndrome, and an uncontrolled generalized inflammatory process are considered. Taking into account the mechanisms for the implementation of these processes, ways to correct these disorders with the help of endothelial protectors, in particular, by prescribing the drug sulodexide, are given.