Etiopathogenic correlations between age-specific hypogonadism, osteoporosis and urolithiasis at men

Study of age-specific hypogonadism correlation through osteopenia with urolithiasis at men is a new perspective direction uniting endocrinology and somatic urology. Besides comparison groups patients observed in the urological clinic of Omsk State Medical Academy have been included in one-stage continuous research. The method of stratification has allowed distinguishing two groups: group of men with urolithiasis - 140 patients and comparison group - 30 men without urolithiasis. Research methods have included questioning of patients by means of questionnaire AMS and international erectile function index, estimation of body weight index, biochemical indicators of blood serum, general testosterone, ionized calcium, densitometry. Occurrence of hypogonadism at men with urolithiasis has accounted 57,1 % (80 patients), in comparison group (men without urolithiasis) it has accounted 23,3 % (7 patients). Occurrence of decrease in mineral density of bone tissue has been statistically and significantly higher at patients with hypogonadism that proves interrelation of osteo-calcium metabolism disturbances and urolithiasis development. The 1st group has accounted 8,7 % of patients with osteoporosis, the 2nd group - 3,3 %. The 1st group has accounted 70,0% of patients with osteopenia, the 2nd group - 25,0%. Level of testosterone is associated with degree of expressiveness of decrease in mineral density of bone tissue. The lowest indices of testosterone have been at men with osteoporosis. Revealed correlations have shown adverse influence of hypogonadism not only on the sexual status of patient, but also on condition of osteo-calcium metabolism, disturbances of which may cause urolithiasis.