Key etiopathogenetic features of formation of uterine myoma

The steady growth of proliferative diseases from year to year is becoming more and more medical and social importance, which is associated with their clinical manifestations and recurrent course, adversely affect the quality of life and the ability to work of women. Uterine fibroids are the most common benign neoplasm in women of reproductive age. This article discusses the key issues of the etiopathogenesis of uterine fibroids. Uterine fibroids are a monoclonal hormone-sensitive neoplasm and are the most common tumour of the reproductive organs of women. The pathogenesis and developmental mechanisms of uterine fibroids today are complex and not fully understood. Perhaps the underlying theory is the ‘clonal expansion of uterine fibroids’, it is the clonal expansion that initiates the processes of neoangiogenesis, activated by tumor growth. Although to this day there remain many controversial and unresolved issues.