Clinical case of medicine-resistant nephrotic syndrome

Nephrotic syndrome is a clinical symptom complex, including proteinuria, edema, hypoalbuminemia, hyperlipidemia. The disease occurs at any age (in children more often between the ages of 2 and 5 years). Significantly more often nephrotic syndrome occurs among the adult population. In patients aged 18 to 35 years, nephrotic syndrome develops in 27-40 % with glomerulonephritis. Nephrotic syndrome belongs to the group of glomerular diseases. According to the nature of the course, episodic, persistent and progressive variants of nephrotic syndrome are distinguished. When evaluating modern approaches to the treatment of nephrotic syndrome, it should be noted that, despite the introduction of modern drugs into clinical practice, the problem of treating nephrotic syndrome has not been fully resolved to date, since a number of patients develop serious complications. A young patient presented with a case of developing medicine-resistant nephrotic syndrome, which is rarely observed in clinical practice. The article describes the characteristics of the nephrotic syndrome, considers the course of the disease, analyzes the data of laboratory and instrumental studies performed on the patient in dynamics in various clinics.