Clinical and diagnostic study of cerebrospinal fluid parameters in the laboratory of the regional children's hospital

The aim of the work is to analyze the morbidity of children who underwent CSF research for the period 2019-2021, as well as to consider the dynamics of the development of the disease picture with purulent and serous meningitis (against the background of anti-intoxication and antibacterial therapy) and to assess the condition of a sick child. The contingent of subjects is an experimental group of children under 14 years old with a diagnosis of purulent and serous meningitis who were being treated at the Penza regional Hospital. The main results of the work showed that in three years the number of children in need of cerebrospinal fluid examination has decreased. However, the number of pathological studies in children with meningitis remained at a fairly high level. In children during the newborn period with a diagnosis of purulent meningitis, there is a positive dynamic of indicators against the background of anti-intoxication and antibacterial therapy. In children diagnosed with serous meningitis, there was a slight lymphocytic pleocytosis, in several cases of the disease there is an increase in neutrophils. This indicates the most severe course of the disease and has a less favorable prognosis.