Investigation of сlinic and immune status in children with rotavirus infections

Modern diagnostic approaches to verification of activators proves a dominating role of rotavirus infection in structure of sharp intestinal infections in children. The analysis of clinical displays, parameters the subpopulation structure of immunocompetent cells, a level cytocin of peripheral blood in children sick of rotavirus an intestinal infection is lead. Allocated at children of Chelyabinsk rotavirus belonged to the most widespread in the world combinations G and P-types: G1P [8], G2P [4], G4P [8] with prevalence G1P [8] genotypes. Weight rotavirus infections defined syndromes of a toxicosis mainly at 2-3 years children. At children with insufficient production IFN-y and IFN-a a background of deficiency IL-1a, IL-1 ß heavy, rough current rotavirus infection was observed.