Clinical, epidemiological and genetic characteristics of acute leukemias in adult clinic of Novosibirsk city hematology center
Автор: Kovynev I.B., Pospelova T.I., Tarnovskiy R.V., Tairova S.A., Agakishiev M.M., Mishenin A.V., Shamaeva G.V., Ovchinnikov V.S., Kolesnikova M.A., Mezit E.V.
Журнал: Сибирский журнал клинической и экспериментальной медицины @cardiotomsk
Рубрика: Лабораторные и экспериментальные исследования
Статья в выпуске: 2 т.32, 2017 года.
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On the basis of the morbidity rate of various forms of acute leukemia was determined for the 10 year post-hoc analysis in Novosibirsk and Novosibirsk region. immunophenotypic characteristic of acute leukemia of patients living on this territory was made. The structure of genetic and molecular genetic abnormalities occurring in blast cells in case of acute myeloid and lymphoid types of leukemia was surveyed. The Correlation of recurrent variants of acute leukemia in accordance with genetic and biomolecular criteria of The World Health Organization (WНO) classification was determined. The meaning of data of molecular genetic (FISH and mycroarrey genochipping) research studies for scoring perspective of treatment and prognosis of disease was shown.
Post-hoc analysis, acute leukemia, immunophenotyping, molecular genetic anomalies, who, fish, genochiping
Короткий адрес: https://sciup.org/14920203
IDR: 14920203
