Clinical and epidemiological aspects of luminal breast cancer and possible ways of its prevention

The objective of the study is to examine the peculiarities of the luminal breast cancer (LBC) development in patients at different reproductive age considering various internal and external factors Materials and Methods. The study included 850 LBC patients with failures of the menstruation. The information on the risk factors was obtained through examination, questionnaire, interview, and history study. Software packages «Statistical 7.0» and Medical (9.3.5.0) were used for data analysis. Results. Patients with LBC type A, in comparison with patients with other LBC types, had more cases of hyperglycemia (F=3.68103, p=0.012648), hypercholesteremia (F=2.10306, p=0.030929), diabetes mellitus (F=3.18476, p=0.021598), hypertension (F=2.83759, p=0.039285), primary sterility (F=1.804980, p=0.046555), large number of pregnancies together with induced abortions (F=3.039890, p=0.029483). No significant special risk factors were identified for LBC type B. Conclusions. LBC type A in peri- and postmenopausal women is mainly the “hormone-dependent metabolic” cancer. The correction of hormone-metabolic disorders and lifestyle in patients after special LBC type A treatment can lower the risk of LBC recurrence.