Clinical, morphological, age and gender characteristics of patients with gastroduodenal ulcerative bleeding

Gastric ulcer and duodenal ulcer continue to be a pressing issue in modern gastroenterology. The prevalence of the pathology increases every year despite the revision of the pathogenetic mechanisms underlying gastroduodenal ulcers, the optimization of approaches to their conservative treatment, and the development of the modern pharmaceutical industry in recent years. Objective. The aim of the study is to identify clinical, morphological, age and gender characteristics in patients with gastroduodenal ulcerative bleeding. Materials and Methods. The study involved 204 patients with gastroduodenal ulcerative bleeding, including 136 (66.7 %) men and 68 (33.3 %) women. The average age of patients was 56.6±17.0. Results. On average, men were younger than women. Ulcers were predominantly duodenal and more common in males. Coronary artery disease was more common among the study patients than in the general population. There was a correlation between bleeding severity (according to Forrest classification) and esophagogastroduodenoscopy duration, which may be related to the time treatment commenced. The assessment of bleeding risk factors (gender, ulcer location, size, and bleeding activity) confirmed the significance of gender and ulcer location. Conclusions. Coronary artery disease treated with aspirin increases the risk of ulcerative gastrointestinal bleeding. Delayed endoscopic examination may lead to a decrease in the incidence of diagnosed Forrest I hemorrhage and an increase in Forrest II hemorrhage. The severity of blood loss significantly impacts mortality rates. Severe blood loss is more common in women with duodenal ulcer.