Clinical and morphological characteristics of chronic duodenitis in children

The research goalis to determine clinical, endoscopic and morphological signs of chronic duodenitis in children.Materials and methods:The diagnostic value of molecular markers has been revealed by immunohistochemical re-search of biopsy. It has been received from endoscopic examination of 32 children aged from 3 to 17 years old withchronic duodenitis. Morphometric investigation of markers expression has been carried out by means of analyzingsystem of digital images of Mikrovizor medical μVizo-103.Results:The index of proliferation has been higher in cells ofcover epithelium than in glands. The inductor expression of apoptosis Bax has been poorly expressed in both groupsof patients. It has been proved that proliferative processes are predominant in this pathology.Conclusion:It has beenfound out that proliferation of significant activity in the cover epithelium accompanies the development of preatrophicprocesses in children with chronic duodenitis. The greater degree of regeneration has been marked in crypts.