Hypertension and diabetes mellitus: clinical and pathogenetic features and state-of-the-art high-tech treatment capabilities (review)

This paper discusses the clinical and pathogenetic aspects of hypertension comorbid with type 2 diabetes mellitus. The role of sympathetic hyperactivation in the mechanisms of this comorbidity and the damage to target organ are reviewed. Authors analyze the capabilities of endovascular renal artery denervation and discuss the mechanisms of therapeutic effect of this procedure. The article is intended for cardiologists, therapists, endocrinologists, and endovascular surgeons.