Clinical-pathological Changes in Reproductive Age Women With Autoimmune Thyroiditis

Research relevance: Autoimmune pathology of the thyroid gland is one of the urgent problems of modern endocrinology, and this is due to the lack of clarity of pathogenetic mechanisms and the lack of objective and reliable diagnostic methods, including immunological. The mechanisms of autoimmune thyroid diseases have not yet been fully elucidated, although about a hundred years have passed since the first description of autoimmune thyroiditis. According to world statistics, thyroid disease occurs in almost 30% of the world’s population. According to the latest data, in Kyrgyzstan, they are found in 10–30 percent of the population. Objectives of the study: Clinical and pathological substantiation of ways to optimize the diagnosis of autoimmune thyroiditis in residents of the southern region of the Kyrgyz Republic. Research methods: clinical and immunological (determination of the titer of antibodies to thyroid peroxidase (AT TPO); cytokines); static method; laboratory (content of free thyroxine (T4); thyroid-stimulating hormone (TSH); free triiodothyronine (T3); hematological, biochemical blood test; ultrasound of the thyroid gland. Conclusions: Lack of iodine causes irreparable harm to absolutely every person: child and adult, men and women. Iodine deficiency is most common in women who are in late pregnancy.