Combined modality treatment of stenosed rectal cancer

The program of the combined modality treatment of stenosed rectal cancer (SRC) with the use of various regimens of preoperative radiation therapy and endoscopic technologies directed to tumor obstruction correction has been worked out. A total of 156 patients with SRC were included into the study. The study group comprised 88 patients who received preoperative radiation therapy after restoring rectal passage. The control group consisted of 68 patients who underwent surgery without preliminary correction of tumor stenosis followed by postoperative radiation therapy. Endoscopic technologies make it possible to admimster neoadjuvant treatment and to reduce the risk of obstructive surgery by 33,2 % not adversely effecting on short-term results of surgical treatment. Preoperative radiation therapy significantly increased the 5-year recurrence-free survival rate for patients with SRC being 71,7 % for stage II and 33,6 % for stage III. The 5-year survival rates in the control group were 50,2 % and 15,2 %, respectively (p