Comprehensive assessment of the formation factors of allergic rhinitis in children with bronchial asthma

Bronchial asthma (BA) and allergic rhinitis (AR) are comorbid diseases, which is associated with the histological, physiological and immunopathological similarities of the upper and lower respiratory tract, systemic mechanisms of the development of chronic allergic inflammation. Patients with AR are 3 times more likely to develop asthma than healthy individuals, and, as a rule, rhinitis precedes BA in 32-49% of patients. Many patients with AR have bronchial hyperreactivity (HRH), which indicates that the presence of rhinitis is a risk factor for the development of AD.