Concentration of catecholamines in the blood and evaluation of the effectiveness of anesthesia

We conducted a comparative study of the dynamics of perioperative changes in the concentrations of catecholamines in the blood of patients with occlusive lesions of the main arteries with two types of the most commonly used types of anesthesia - combined general inhalation anesthesia with fluorotane and regional anesthesia. The study of the catecholamine status in patients with occlusive lesions of the main arteries during reconstructive operations under combined general anesthesia with fluorotane and regional anesthesia in the perioperative period showed that there was tension of the hormonal link of the sympatho-adrenal system, which is confirmed by doubled concentrations of adrenaline in the blood. A high level of endogenous adrenaline in the blood indicated the presence of a humoral reaction of the body to operational stress caused by sympathicotonia, which was practically not affected by the types of anesthesia used. However, the effects of hyperadrenalemia were perioperatively blocked by general and regional anesthesia. Observation of the concentrations of catecholamines in the blood at the stages of reconstructive operations on the main arteries of the lower extremities allowed us to note greater stability of the perioperative period with regional anesthesia methods.