Correlation of the zinc level in the spermoplasm with the fertility characteristics of human ejaculate

Background: Zinc is essential for the normal functioning of the male reproductive system. The data on the diagnostic value of the zinc level in the human spermoplasm and its relationship with the main parameters of the sperm fertility are contradictory. Aim: study of the correlations between the zinc level in the spermoplasm and the spermogram characteristics. Methods: The sperm of men of the reproductive age (n=486, average age 33.07±3.03 years) was studied. In addition to the standard spermogram, MAR tests (IgA, IgG and IgM) were performed in the sperm samples, the degree of fragmentation of the sperm DNA, the sperm interaction with hyaluronic acid, the acrosine activity, and the neutral alpha-glucosidase activity were assessed, the citric acid, fructose and glycodelin levels were determined, and the level of reactive oxygen species was studied. The zinc level determination in the spermoplasm was carried out by a standard spectrophotometric method with 5-Br-PAPS chromogen. The Pearson's formula was used for the correlation analysis. The study was conducted from 2018 to May 2022, once. Results: A significant negative correlation of the zinc level in the spermoplasm with the age of men was revealed (r=-0.16; p function show_eabstract() { $('#eabstract1').hide(); $('#eabstract2').show(); $('#eabstract_expand').hide(); }