«Pabisorb» preparation theraupevtic and prophylactic activity at colibacteriousis and external g γ- irradiated animals

The performed investigation showed that Escherichia -based infection along with radiogenic stress is characterized with infection process aggravation accompanied by summing pathogen affecting factors (additive affect) having hemotoxic, oxidation effect, apoptotic destruction of immunocompetent and hemogoethic cells, lack of antioxidant security system thus causing higher death rate by exposure to two pathogen kinds. Parenteral and oral application of the “Pabisort” composite preparation based on polyclonal antibodies (poliglobulins), beekeeping products, probiotic microorganism metabolites and mineral sorbent resulted in modification of radiation and biological exposure with increased survival rate of animals both infected with escherichiosis and radiation sickness by inhibiting pathogen hematotoxic, oxidating, apoptotic and immunotoxic effect.