Brain lymphoma: clinical case description

Relevance. Differential diagnosis between the brain infectious lesions and the central nervous system (CNS) oncological diseases is an urgent task in infectology.The aim of the study is to present and analyze a primary diffuse large-cell B-cell lymphoma of the central nervous system clinical case.Materials and methods. The work was carried out on the basis of the clinic and the Department of Infectious Diseases with Epidemiology of SamSMU. A clinical case of primary diffuse large-cell B-cell lymphoma of the central nervous system is presented. The patient's brain CT and MRI, cerebrospinal fluid studies were performed, general clinical, biochemical, and serological diagnostic methods were used.Results. The article describes a primary diffuse large-cell B-cell lymphoma of the central nervous system clinical case in a patient admitted to an infectious hospital with a directional diagnosis of unspecified etiology acute serous meningoencephalitis.Conclusions. Differential diagnosis between infectious brain lesions and CNS oncological diseases manifesting with cerebral and meningeal syndromes is a difficult task for an infectious disease specialist. A comprehensive examination allows for a diagnostic search for infectious and tumor diseases of the central nervous system, to establish a final diagnosis and to develop tactics for further patient management.