Magnetic resonance imaging of the brain in patients with multiple sclerosis: treatment with immunomodulatory drugs

The analysis of the results of immunomodulatory drug-based treatment of multiple sclerosis (MS) with calculation of the volume of tissue damage and the use of magnetic resonance imaging (MRI) at control stages is presented. The article describes the diagnostic MRI criteria of loci of brain tissue damage and their temporal changes in MS during the follow-up period for as long as up to 2 years. The contrast-enhanced study with paramagnetic agent not always enables detection of the presence of MS progression whereas the changes in the number and area of hot spots as well as their migration may be more indicative of worsening of the disease compared with the results of the contrast-enhanced study.