Management of innovations in scientific instrumentation

Автор: Slepak Boris Semyenovich, Slepak K.B.

Журнал: Научное приборостроение @nauchnoe-priborostroenie

Статья в выпуске: 4 т.27, 2017 года.

Бесплатный доступ

Breakthrough scientific research in the field of molecular genetic analysis, which refers to a risky, significant funding for state organizations, is described. Scientific instruments illustrating the development of one of the most promising areas of scientific instrumentation, which allows the creation of small-scale analytical systems with modern software for rapid analysis of a large variety of biological samples, are presented.

Biological sample, dna sequencer, micro fluidic chip, polymerase chain reaction, fluorescence, capillary

Короткий адрес: https://sciup.org/142214826

IDR: 142214826 | DOI: 10.18358/np-27-4-i107117

Список литературы Management of innovations in scientific instrumentation

Slepak K.B. The development of the scientific and educational potential of Russia’s regions in the process of innovative import substitutiony//Economics and management. 2015. No. 7. P. 84-91.
Slepak K.B. The development of science, education and innovative technologies in the regions of Russia as a factor in ensuring national security. SPb.: Publishing house of Polytechnic University, 2014. 192 p. ISBN 978-5-7422-4577-3.
Meeting of the Governmental Commission on Import Substitution . URL: http://government.ru/news/19937/.
Fedorov A.A., Sochivko D.G., Varlamov D.A., Kurochkin V.E. Extended kinetic model of real-time polymerase chain reaction process//Journal of Physics: Conference Series. 2016. Vol. 769, no. 1. 012019 DOI: 10.1088/1742-6596/769/1/012019
Fedorov A.A., Berdnikov A.S., Sochivko D.G., Varlamov D.A., Kurochkin V.E., Petrov R.V. Approximate analytic solution of a simple system of kinetic equations describing the enzymatic synthesis of nucleic acids//Doklady Biochemistry and Biophysics. 2016. Vol. 470, no. 1. P. 379-382 DOI: 10.1134/S1607672916050185
Belenky B.G., Evstrapov A.A., Kozulin R.A., Konovalov S.V., Kurochkin V.E. Fluorimetric detector. RF patent issued 10 May, 2002, granted No. RU 2182329. (In Russ.).
Status of the Microfluidics Industry 2017. URL: https://www.i-micronews.com/category-listing/product/status-of-the-microfluidics-industry-2017.html
Agilent. URL: http://www.genomics.agilent.com.
Fluidigm. URL: http://www.fluidigm.com/biomark-system.html.
Appliedbiosystems. URL: http://appliedbiosystems.com.
Shen F., Du W., Kreutz J.E., Fok A., Ismagilov R.F. Digital PCR on a SlipChip//Lab Chip. 2010. Vol. 20, no. 10. P. 2666-2672.
Guo M.T., Rotem A., Heymanab J.A., Weitz D.A. Droplet microfluidics for high-throughput biological assays//Lab Chip. 2012. No. 12. P. 2146-2155.
BIO-RAD QX200™ Droplet Digital™ PCR System. URL: http://www.bio-rad.com/ru-ru/product/qx200-droplet-digital-pcr-system.
Raindance Technologies Inc, USA. RainDrop® Digital PCR System. URL: http://raindancetech.com/digital-pcr-tech/raindrop-digital-pcr-system/.
Bulyanitsa A.L., Posmitnaya Y.S., Rudnitskaya G.E., Lukashenko T.A., Tsymbalov A.I., Evstrapov A.A. Glass and polymer microfluidic chips for electrophoretic separation of biomolecules//Nauchnoe Priborostroenie . 2014. Vol. 24, no. 4. P. 67-76.
Kukhtevich I.V., Belousov K.I., Bukatin A.S., Chubinskiy-Nadezhdin V.I., Vasileva V.Y., Negulyaev Y.A., Evstrapov A.A. Microfluidic Chips for the Study of Cell Migration under the Effect of Chemicals//Technical Physics Letters. 2016. Vol. 42, no. 5. P. 478-481.
Belousov K.I., Filatov N.A., Evstrapov A.A., Kukhtevich I.V., Bukatin A.S. The study of mixing of reagents within a droplet in various designs of microfluidic chip//Journal of Physics: Conference Series. 2016. Vol. 741, no.1. 012052.
Bukatin A.S., Mukhin I.S., Malyshev E.I., Kukhtevich I.V., Evstrapov A.A., Dubina M.V. Peculiarities in the formation of microstructures with a high aspect ratio in preparing polymer microfluid chips for in vitro analysis of single living cells//Technical Physics. 2016. Vol. 61, no. 10. P. 1566-1571.
Evstrapov A.A., Bulyanitsa A.L., Rudnitskaya G.E., Lukashenko T.A., Tupik A.N., Tsymbalov A.I., Esikova N.A., Posmitnaya Y.S. Evaluation of the results of a real-time polymerase chain reaction of cDNA of CK19 tumor markers by electrophoresis on a microfluidic chip//Nauchnoe Priborostroenie . 2012. Vol. 22, no. 4. P. 17-25.
Evstrapov A., Esikova N., Rudnitskaya G., Antropova T.V. Porous glasses as a substrate for sensor elements//Optica Applicata. 2010. Vol. XL, no. 2. P. 333-340.
Esikova N.A., Evstrapov A.A., Bulyanitsa A.L., Antropova T.V. Study features of the change of the fluorescence signal of the sensor element based on porous glass on the concentration of labeled insulin//Glass Physics and Chemistry. January 2015. Vol. 41, no. 1. P. 89-92. (ISSN: 1087-6596).
Order No. 543 of the FASO of Russia dated November 3, 2015 "On the Council for Scientific Instrumentation of the Federal Agency for Scientific Organizations".

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