Mathematical modeling of the optoacoustic signal from aggregated erythrocytes to assess the level of aggregation

The presented model of the formation of an optoacoustic signal under the influence of an Nd: YAG laser on model blood samples with aggregated erythrocytes, to study how the amplitude of the optoacoustic (OA) signal and the power spectrum will vary depending on the level of aggregation of erythrocytes. A mathematical model of the packing of erythrocytes has been developed for modeling the aggregation of red blood cells. It is established that the amplitude of the optoacoustic signal increases with increasing aggregation level and the frequency of the spectral power of the signal decreases.