Mechanism of aromatic compound acylation in Friedel-Krafts reaction

Автор: Stepacheva Antonina, Dmitrieva Anastasia

Журнал: Бюллетень науки и практики @bulletennauki

Рубрика: Химические науки

Статья в выпуске: 2 (15), 2017 года.

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In current work the mechanism of Friedel-Krafts acylation reaction of aromatic compounds is studied. While producing aromatic ketones, the substrate undergoes the interaction with acylchloride in the presence of a catalyst. The reaction is initiated by the formation of donor/acceptor complex. In some scenarios carbonylation as a side reaction can occur. Current work reviews the synthesis of [2.2]cyclophane according to Crame and Truesdale as an example of acylation application in complex molecules synthesis as well as the reactivity of different aromatic compounds in Friedel-Krafts reactions.

Friedel-krafts reaction, acylation, mechanism

Короткий адрес: https://sciup.org/14111478

IDR: 14111478   |   DOI: 10.5281/zenodo.291821

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