Mechanisms and clinical significance of nephroprotective action of sodium-glucose cotransporter 2 inhibitors

Автор: Pchelin I.Y., Vasilkova V.N., Shishkin A.N., Bayrasheva V.K., Hudiakova N.V.

Журнал: Juvenis scientia @jscientia

Рубрика: Медицинские науки

Статья в выпуске: 1, 2019 года.

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The issue of mechanisms and clinical significance of nephroprotective action of sodium-glucose cotransporter 2 (SGLT2) inhibitors is dealt with. Discussed are the manifestations related to the following effects of the members of this pharmacological group: their influence on glomerular filtration rate, glycaemia, diuresis, ketogenesis and other factors. The results of recent experimental and clinical studies revealing particular aspects of nephroprotective action of SGLT 2 inhibitors in type 2 diabetes mellitus and other pathological conditions are analyzed.

Ингибиторы sglt2, diabetes mellitus, oral hypoglycemic agents, sglt2 inhibitors, chronic kidney disease, diabetic nephropathy, nephroprotection

Короткий адрес: https://sciup.org/14113478

IDR: 14113478   |   DOI: 10.32415/jscientia.2019.01.01

Статья научная