Mechanisms of cobalt chloride toxic influence on biochemical and functional indicators in experiment

It is established that ecotoxicants induce formation of active forms of oxygen (AFO) and peroxide oxidation of lipids (POL), oppressing thus activity of superoxidysmutase (SОD). The secondary product of POL – malonic dialdehyde (МДА) causes structurally functional changes of phospholipids of cellular membranes of [1] internal organs: nephros, hepatos, and myocardium that is accompanied by oppression of activity Na +, K +-ATP-ase in homogenates of cortical, brain substance of nephros, hepatic and myocardial tissues.