Metachronic malignant tumors in patients radically operated on for gastric cancer

Metachronic primary-multiple malignant tumors were detected in 64 (52,2 %) of gastric cancer patients and in 17 (8,2 %) of cases with early gastric cancer. Colon tumors were the most common among metachronic tumors (15 %), followed by breast tumors (9 %) and lymphoproliferative disordes (9 %). In cases when secondary tumor occurred earlier, locally advanced gastric cancer was diagnosed as a rule. Secondary metachronic tumors were most frequently observed after treatment for early stages of gastric cancer. Radical treatment for the secondary tumor was performed in 52 (81 %) cases and palliative and symptomatic treatments in 12 (19 %) of cases. Surgical and combined modality treatment methods were used most frequently. Polyneoplasia was shown not to be contraindication to radical surgery including combined modality treatment. Tumors developed after treatment for gastric cancer were the main cause of death for these patients. During follow-up it is necessary to exclude not only recurrences and metastases but also metachronic tumors considering findings on their predominant localizations.