Method of controlled transosseous osteosynthesis. Structure and basic concepts of biochemical and metabolic processes in dynamics of treatment of patients with chronic osteomyelitis

Aim. To evaluate correlation of carbohydrate metabolism processes in the organism during chronic osteomyelitis therapy using the method of controlled transosseous osteosynthesis according to Ilizarov method. Materials and methods. Blood serum chemistry value of 39 patients with chronic osteomyelitis aged from 18 to 56 years old was studied. All patients were treated using the method of bilocal distruction osteosynthesis. The following parameters of blood serum were studied: the activity of lactate dehydrogenase, creatinekinase, content of adenosine-triphosphate (ATP), concentration of glycolysis, lactate and pyruvate final products. Glycolysis systematic index was used. Results. During treatment the elevated concentration of glycolysis products was found in the blood serum of patients. Conclusion. The character of changes of blood serum biochemical parameters in patients with chronic osteomyelitis depended on the choice of surgical procedures volume. Bone defect restoration did not lead to significant metabolic disorders.