Dual-isotope myocardial spect technique with 99mTc-mibi and 123I-BMIPP

The aim of this study was to demonstrate the capabilities of the dual-isotope SPECT with 123I-BMIPP and 99mTc-MIBI in the assessment of myocardial perfusion-metabolic relationships. Following 70 min after the intravenous administration of 99mTc-MIBI (296 MBq), 123I-BMIPP (111 MBq) was introduced. The images were recorded using SPECT system equipped with solid-state semiconductor cadmium-zinc-telluride detectors. The energy windows of the differential discriminator for 99mTc and 123I were adjusted to avoid overlapping. This enables to perform the dual-isotope myocardial scintigraphy as a single procedure at the same day. This method allows for the reduction of radiation exposure and procedure duration, improves logistics of in-hospital examination of patients, and makes the procedure for assessment of myocardium metabolism and perfusion more comfortable.