Public health risk assessment methodology under the influence of chemical, physical and biological factors for defining products (goods) safety indicators

The article describes a fundamental algorithm and methods for health risk assessment of consumer products. The methodology is based on the classical risk assessment scheme, which includes the steps of hazard identification, exposure assessment, establishment of dependency “exposure-response”, and risk characterization. The key feature of the developed approaches is the use of risk evolution mathematical modeling, based on the adaptation to the risk assessment problems of the paired dependency “factor (exposure) - response” obtained in epidemiological studies of various levels. Evolutionary model of violations in the organs and systems of the body when consuming production is a mathematical description of the process of changing the consumers’ health status, under the action of complex hazards inherent in products for a long time against the background of natural aging. The approaches to the overall risk assessment generated by production heterogeneous factors are proposed. The techniques for risk structuring have been described. The scale for assessing risk, harmonized with internationally recognized counterparts, is proposed. The methodology is developed for the tasks of the Customs Union, is universal and can be used for a wide range of tasks. The methodology was tested in the justification of the food safety and risk assessment criteria, formed for durable production such as furniture, building and finishing materials.