Methodology for local skin edema calculating in breast cancer

Breast cancer with skin involvement is one of the least studied and at the same time difficult to treat forms of cancer. Despite the achievements of modern diagnostics, many issues related to skin edema severity evaluation and quantitative assessment of changes associated with neoadjuvant drug therapy often cause a number of difficulties. In turn, this can lead to both incorrect staging and «overtreatment» of patients, as well as subjectivity in assessing the response to the treatment. Various approaches have been proposed to calculate the severity of edema, but they have not been widely accepted. This article presents our method developed for determining the area of skin edema, which in the future will allow individualizing approaches to treatment.