CONSTRUCTION OF AN OPTICAL COAGULOMETER SYSTEM AND WAYS TO REDUCE INTERFERENCE

The latest standards of laboratory diagnostics of hemostasis involve the study of micro–samples — tens of microliters, however, the analysis of such small volumes is a difficult task. It is necessary to minimize the interference associated with not only the device electronics, but also the optical node. The article suggests some ways to reduce interference when designing the optical system of coagulometers. The reasons for the appearance of these interferences from the point of view of physics and optics are presented. The method of determining the optimal wavelength for hemostasis tests is described, recommendations are given on the choice of emission sources and photodetectors. The design of a thermostatically controlled plate and measuring channels is proposed. An experiment has been conducted that clearly shows the effectiveness of the proposed methods for reducing interference.The influence of various factors and design features on the useful output signal is described.