Microbiological studies of clinical material as a stage of prophylaxis of periprosthetic infection after arthroplasty of large joints

The purpose of the study is to analyze the frequency of positive culture of biomaterial in patients with primary and revision of large joint arthroplasty; identify discrepancies between the results of sowing of puncts before surgery and sowing of intraoperative biomaterial; comparison of the results of sowing of synovial fluid in the bacteriological laboratories at the place of residence with the data of the laboratory of Federal center for traumatology, orthopedics and endoprosthetics of the Ministry of health of Russia (Cheboksary); analysis of the microbiological landscape of pathogens of infectious complications. The material of the study was the results of microbiological examination of 12847 samples of biomaterial from 5881 patients taken in 2015-2017 (punctates from the joint cavity, tissue bioptates, washouts from remote components of prostheses, spacers and other metal structures). The study group consisted of patients who needed primary endoprosthetics and who had a history of 4 or more risk factors for the development of infectious complications (6433 samples, of them positive - 3); received for revision of the endoprosthetics (2991 samples, of them 414 were positive); having metal structures in the field of surgical intervention or condition after their removal (1631 samples, and they are positive - 15); having a history of purulent process in the field of planned surgical intervention (1792 samples)...